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KMID : 0381219750070080521
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Journal of RIMSK
1975 Volume.7 No. 8 p.521 ~ p.532
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The Clinical Use of Polymethyl Methacrylate in Total Joint Replacement
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Abstract
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With great impressive clinical benefits from total joint replacement to severely crippled patients, that is, pain relief with useful range of motion, some pertinent and ingenious orthopedic surgeons open the era of prosthesis in orthopedic field.
The major technical difficulties in fixation of prosthesis in bone is overcomed greatly with introducing "self curing polymethyl methacrylate" as a bone cement.
But there were numerous problems, solved or unsolved, in clinical application of the bone cement with its possible toxicity to patients as the residual monomer in polymerized cement, leached out from its mass and absorbed into the blood stream, was proved experimentally to be harmful in large amount.
The knowlege of chemical and physical properties and behavior in vivo is mandatory in proper clinical application of bone cement.
With available medical literatures, the progress in clinical and experimental studies of the polymethyl methacrylate is discussed.
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